Description

1-(2,3,4,6-Tetrafluorobenzyl)-1H-Pyrazol-4-Amine is a high-value fluorinated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring a tetrafluorobenzyl group, is engineered to confer unique electronic and steric properties, making it indispensable for creating novel compounds with targeted functionalities. This intermediate is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new agrochemicals, pharmaceuticals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, liquid crystals, or organic electronic materials with specific optical or electrical properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems, leveraging the pyrazole amine for conjugation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2,3,4,6-Tetrafluorobenzyl)-1H-Pyrazol-4-Amine
CAS No.	1002032-97-4
Molecular Formula	C10H7F4N3
Molecular Weight	245.18 g/mol
Synonyms	1H-Pyrazol-4-amine, 1-[(2,3,4,6-tetrafluorophenyl)methyl]-; 1-(2,3,4,6-Tetrafluorobenzyl)-1H-4-aminopyrazole; 4-Amino-1-(2,3,4,6-tetrafluorobenzyl)-1H-pyrazole; 1-(Tetrafluorobenzyl)-1H-pyrazol-4-amine; 1-(2,3,4,6-Tetrafluorobenzyl)-4-aminopyrazole; 4-Amino-1-(2,3,4,6-tetrafluorobenzyl)pyrazole
EINECS	Contact for details

Quality Control

Our production of 1-(2,3,4,6-Tetrafluorobenzyl)-1H-Pyrazol-4-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support cGMP-compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.