Description

Methyl 2-Bromo-3-(4'-Fluorophenyl)-3-Oxopropanoate is a high-purity, specialized organic building block used in advanced chemical synthesis. This compound is valued for its reactive bromo and keto ester functionalities, which enable precise molecular construction in complex organic frameworks. It is primarily required by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the fluorophenyl moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Employed in the creation of tagged molecules and probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 2-Bromo-3-(4'-Fluorophenyl)-3-Oxopropanoate
CAS No.	1001922-15-1
Molecular Formula	C10H8BrFO3
Molecular Weight	275.07 g/mol
Synonyms	Methyl 2-bromo-3-(4-fluorophenyl)-3-oxopropanoate; 2-Bromo-3-(4-fluorophenyl)-3-oxopropanoic acid methyl ester; Methyl α-bromo-β-oxo-4-fluorohydrocinnamate; 4-Fluorophenyl 2-bromo-3-methoxy-3-oxo-1-propen-1-yl ketone; Propanedioic acid, bromo(4-fluorophenyl)-, methyl ester; 1001922-15-1; Methyl bromo(4-fluorobenzoyl)acetate
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-3-(4'-Fluorophenyl)-3-Oxopropanoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the exacting standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.