Description

(4-Nitro-Pyrazol-1-Yl)-Acetonitrile is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key precursor for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the reactivity of the nitropyrazole moiety.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in research for synthesizing organic electronic materials and dyes.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring complex, functionalized heterocycles.

Basic Information

Product Name	(4-Nitro-Pyrazol-1-Yl)-Acetonitrile
CAS No.	1001500-47-5
Molecular Formula	C5H4N4O2
Molecular Weight	152.11 g/mol
Synonyms	1-(Cyanomethyl)-4-nitropyrazole; 4-Nitro-1H-pyrazole-1-acetonitrile; (4-Nitro-1H-pyrazol-1-yl)acetonitrile; 1H-Pyrazole-1-acetonitrile, 4-nitro-; 4-Nitro-1-pyrazoleacetonitrile; 1-Cyanomethyl-4-nitropyrazole; Acetonitrile, (4-nitropyrazol-1-yl)-
EINECS	Contact for details

Quality Control

Our (4-Nitro-Pyrazol-1-Yl)-Acetonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.