Description

Psmα3 CAS NO 1001405-52-2 is a synthetic antimicrobial peptide (AMP) analog, representing a significant advancement in the development of novel anti-infective agents. This compound is engineered to mimic the potent, broad-spectrum activity of natural phenol-soluble modulins (PSMs) against drug-resistant bacterial pathogens. It is a critical research-grade material for pharmaceutical R&D, biotechnology, and academic laboratories focused on developing next-generation therapeutics to combat the global antimicrobial resistance crisis.

Application

• Antimicrobial Research & Development: As a lead compound for studying structure-activity relationships (SAR) and optimizing peptide-based antibiotics.
• Mechanism of Action Studies: Investigating bacterial membrane disruption, biofilm inhibition, and immunomodulatory effects.
• Preclinical Pharmaceutical Development: Serving as an active pharmaceutical ingredient (API) intermediate for in vitro and in vivo efficacy testing.
• Biomaterial Coating: Research into surface functionalization for medical devices and implants to prevent bacterial colonization.
• Veterinary Medicine Research: Exploration of novel treatments for bacterial infections in animals.
• Cosmeceutical Applications: Investigation of anti-acne and skin-preserving properties in advanced cosmetic formulations.

Basic Information

Product Name	Psmα3
CAS No.	1001405-52-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Phenol-soluble modulin α3; PSMα3 peptide; Antimicrobial peptide PSMα3; Synthetic Psmα3; Staphylococcus aureus PSMα3 mimetic; Anti-MRSA peptide analog; PSM alpha 3
EINECS	Contact for details

Quality Control

Our Psmα3 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research. Each lot undergoes comprehensive analytical characterization, including purity assessment by HPLC, mass spectrometry (MS) for sequence confirmation, and endotoxin testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a dry environment before opening to prevent condensation. Aliquot into single-use vials to minimize repeated freeze-thaw cycles and exposure to atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.