Description

2-(4-Fluoro-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its exceptional utility as a key reagent in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the 4-fluoro-3-methylphenyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aryl groups.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable and reactive organoboron reagent for forming carbon-carbon bonds with aryl halides or triflates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate fluorinated aromatic systems.
• Liquid Crystal & OLED Material Research: Employed in the creation of advanced organic electronic materials and display components.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules in diagnostic and research applications.

Basic Information

Item	Details
Product Name	2-(4-Fluoro-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1001200-60-7
Molecular Formula	C13H18BFO2
Molecular Weight	236.09 g/mol
Synonyms	4-Fluoro-3-methylbenzeneboronic acid pinacol ester; (4-Fluoro-3-methylphenyl)boronic acid pinacol ester; 2-(4-Fluoro-3-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Fluoro-3-methylphenylboronic acid pinacol ester; 4-Fluoro-m-tolylboronic acid pinacol ester; PINACOL (4-FLUORO-3-METHYLPHENYL)BORONATE
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-3-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.