Description

5,5,5-Trifluoro-n-(4-Fluorophenyl)-4-Hydroxypentanamide is a high-value fluorinated organic compound, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both trifluoromethyl and fluorophenyl groups, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D and process development teams in the pharmaceutical and agrochemical industries for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals that require fluorinated components for specific thermal or optical properties.
• Chemical Biology Probes: Utilized in the design of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring the introduction of specific fluorinated motifs.

Basic Information

Product Name	5,5,5-Trifluoro-n-(4-Fluorophenyl)-4-Hydroxypentanamide
CAS No.	1000778-77-7
Molecular Formula	C11H11F4NO2
Molecular Weight	265.21 g/mol
Synonyms	4-Hydroxy-5,5,5-trifluoro-N-(4-fluorophenyl)pentanamide; 5,5,5-Trifluoro-4-hydroxy-N-(4-fluorophenyl)valeramide; N-(4-Fluorophenyl)-5,5,5-trifluoro-4-hydroxypentanamide; 4-Fluoro-N-(5,5,5-trifluoro-4-hydroxypentanoyl)aniline; 1000778-77-7; 5,5,5-Trifluoro-4-hydroxy-N-(p-fluorophenyl)valeramide; Pentanamide, 5,5,5-trifluoro-4-hydroxy-N-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 5,5,5-Trifluoro-n-(4-Fluorophenyl)-4-Hydroxypentanamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.