Description

2-Amino-3-Bromo-5-Iodobenzonitrile is a high-purity, multi-halogenated aromatic nitrile building block of significant synthetic value. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive halogen and amino functional groups.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions, facilitated by the bromo and iodo substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems.

Basic Information

Product Name	2-Amino-3-Bromo-5-Iodobenzonitrile
CAS No.	1000577-52-5
Molecular Formula	C7H4BrIN2
Molecular Weight	322.93 g/mol
Synonyms	3-Bromo-5-iodo-2-aminobenzonitrile; 2-Amino-3-bromo-5-iodobenzonitrile; Benzonitrile, 2-amino-3-bromo-5-iodo-; 3-Bromo-5-iodoanthranilonitrile; 2-Cyano-6-bromo-4-iodoaniline; 4-Iodo-6-bromo-2-aminobenzonitrile; 2-Amino-3-bromo-5-iodo-benzonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Bromo-5-Iodobenzonitrile is subjected to rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Our quality assurance protocols are designed to support cGMP and ISO guidelines for advanced chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee full traceability and compliance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.