Description

5-Bromo-3-Chloro-2-Iodobenzonitrile is a highly functionalized halogenated benzonitrile derivative, serving as a critical multi-purpose building block in advanced organic synthesis. Its unique substitution pattern offers distinct reactivity and selectivity, making it invaluable for constructing complex molecular architectures. This compound is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional organic materials due to its electron-withdrawing nitrile group and halogen atoms.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Scale-Up: An essential substrate for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Iodobenzonitrile
CAS No.	1000577-40-1
Molecular Formula	C7H2BrClIN
Molecular Weight	372.36 g/mol
Synonyms	2-Iodo-5-bromo-3-chlorobenzonitrile; 3-Chloro-5-bromo-2-iodobenzonitrile; Benzonitrile, 5-bromo-3-chloro-2-iodo-; 5-Bromo-3-chloro-2-iodobenzene carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Chloro-2-Iodobenzonitrile is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.