Description

1,4-Dibromo-2-(difluoromethoxy)benzene is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both bromine substituents and a difluoromethoxy group, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Liquid Crystal Materials: Used in the synthesis of fluorinated aromatic cores for high-performance liquid crystal displays (LCDs) and organic electronic materials.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or host materials in OLED device fabrication.
• Cross-Coupling Reactions: The bromine atoms provide excellent handles for palladium-catalyzed reactions like Suzuki, Negishi, or Buchwald-Hartwig couplings to form complex biaryl structures.
• Fluorine Chemistry Research: An important compound for studying the effects of fluorine and fluorinated alkoxy groups on the physical and chemical properties of aromatic systems.
• Polymer Modification: Can be incorporated as a monomer or modifier to introduce fluorine and bromine into polymer backbones, altering thermal stability and solubility.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	1,4-Dibromo-2-(Difluoromethoxy)Benzene
CAS No.	1000575-26-7
Molecular Formula	C7H4Br2F2O
Molecular Weight	301.91 g/mol
Synonyms	2-(Difluoromethoxy)-1,4-dibromobenzene; 1,4-Dibromo-2-(difluoromethoxy)benzene; Benzene, 1,4-dibromo-2-(difluoromethoxy)-; 1,4-Dibromo-2-difluoromethoxybenzene
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2-(difluoromethoxy)benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by techniques including HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.