Description

2-(4-Methoxy-3-(Trifluoromethyl)Phenyl)Acetic Acid is a high-value fluorinated aromatic building block, prized for its unique combination of methoxy and trifluoromethyl substituents which impart desirable electronic and steric properties. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structure is key to modulating biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the life sciences and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and bioactivity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2-(4-Methoxy-3-(Trifluoromethyl)Phenyl)Acetic Acid
CAS No.	1000566-45-9
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	[4-Methoxy-3-(trifluoromethyl)phenyl]acetic acid; 2-[4-Methoxy-3-(trifluoromethyl)phenyl]ethanoic acid; 4-Methoxy-3-trifluoromethylphenylacetic Acid; α-(4-Methoxy-3-(trifluoromethyl)phenyl)acetic Acid; (4-Methoxy-3-trifluoromethylphenyl)acetic Acid; 3-Trifluoromethyl-4-methoxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Methoxy-3-(Trifluoromethyl)Phenyl)Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment. Our quality commitment supports development from research to commercial scale, with the capability to meet specific customer protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.