Description

Benzeneacetic Acid, 3-(Difluoromethyl)- is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic incorporation of the difluoromethyl group, which can profoundly influence the physicochemical and metabolic properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly where fluorine substitution is used to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and insecticides, leveraging the difluoromethyl moiety to enhance biological activity and environmental profile.
• Material Science Research: Serves as a precursor for fluorinated monomers or ligands in the development of specialty polymers, coatings, and advanced materials with unique properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies engaged in custom synthesis projects for clients in life sciences.

Basic Information

Product Name	Benzeneacetic Acid, 3-(Difluoromethyl)-
CAS No.	1000547-15-8
Molecular Formula	C9H8F2O2
Molecular Weight	186.16 g/mol
Synonyms	3-(Difluoromethyl)phenylacetic acid; 2-[3-(Difluoromethyl)phenyl]acetic acid; m-(Difluoromethyl)phenylacetic acid; α-(3-Difluoromethylphenyl)acetic acid; (3-Difluoromethylphenyl)acetic acid; Benzeneacetic acid, 3-(difluoromethyl)-; 1000547-15-8
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, 3-(Difluoromethyl)- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.