Description

2-Methyl-3-(Trifluoromethyl)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the unique combination of the phenylacetic acid scaffold with methyl and trifluoromethyl substituents, which are critical for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting anti-inflammatory and central nervous system (CNS) agents.
• Agrochemical Synthesis: Serves as a versatile precursor in the manufacture of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty electronic chemicals and advanced display materials due to its aromatic and fluorinated structure.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, Heck) and as a precursor for more complex fluorinated compounds in fine chemical production.
• Chemical Research & Development: Essential for academic and industrial R&D laboratories exploring structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	2-Methyl-3-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1000546-18-8
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	2-Methyl-3-(trifluoromethyl)benzeneacetic acid; [2-Methyl-3-(trifluoromethyl)phenyl]acetic acid; α-(2-Methyl-3-(trifluoromethyl)phenyl)acetic acid; 3-Trifluoromethyl-2-methylphenylacetic acid; 2-Methyl-3-trifluoromethylphenylacetic acid; 2-(2-Methyl-3-(trifluoromethyl)phenyl)acetic acid; (2-Methyl-3-(trifluoromethyl)phenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, store separately from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.