Description

4-Methyl-3-(trifluoromethyl)phenylacetic acid is a versatile aromatic carboxylic acid derivative characterized by its trifluoromethyl and methyl substituents. This compound is a valuable pharmaceutical intermediate and building block in advanced organic synthesis, prized for its ability to impart unique physicochemical properties to target molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a lipophilic, electron-withdrawing aromatic moiety.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of advanced electronic materials and functional dyes.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and amide bond formations to create complex molecular architectures.
• Chemical Research: A valuable reagent in academic and industrial laboratories for exploring new synthetic methodologies and structure-activity relationships.

Basic Information

Product Name	4-Methyl-3-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1000544-72-8
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	[4-Methyl-3-(trifluoromethyl)phenyl]acetic Acid; 2-[4-Methyl-3-(trifluoromethyl)phenyl]acetic Acid; 3-Trifluoromethyl-4-methylphenylacetic Acid; α-Tolyl-3-trifluoromethyl-4-methyl Acetic Acid; (4-Methyl-3-trifluoromethylphenyl)acetic Acid; 4-Methyl-3-trifluoromethylbenzeneacetic Acid; 2-(4-Methyl-3-(trifluoromethyl)phenyl)acetic Acid
EINECS	Contact for details

Quality Control

Our production of 4-Methyl-3-(trifluoromethyl)phenylacetic acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.