Description

3-Chloro-5-Fluoro-4-Methoxyphenylacetic Acid, 97% is a high-purity, substituted phenylacetic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it a valuable intermediate for creating complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the chloro-fluoro-methoxy substitution pattern can enhance biological efficacy and environmental profile.
• Liquid Crystal & OLED Material Research: Serves as a building block for synthesizing specialized organic compounds used in electronic displays and optoelectronic devices.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	3-Chloro-5-Fluoro-4-Methoxyphenylacetic Acid, 97%
CAS No.	1000544-65-9
Molecular Formula	C9H8ClFO3
Molecular Weight	218.61 g/mol
Synonyms	2-(3-Chloro-5-fluoro-4-methoxyphenyl)acetic Acid; (3-Chloro-5-fluoro-4-methoxyphenyl)acetic Acid; 3-Chloro-5-fluoro-4-methoxybenzeneacetic Acid; 3-Chloro-5-fluoro-4-methoxyphenylacetic Acid; 3-Chloro-5-fluoro-4-methoxy-α-toluic Acid; 3-Chloro-5-fluoro-4-methoxybenzeneacetic acid; 3-Chloro-5-fluoro-4-methoxybenzenacetic acid; 3-Chloro-5-fluoro-4-methoxy-phenylacetic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Fluoro-4-Methoxyphenylacetic Acid is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the specified 97% minimum purity and consistent impurity profile. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.