Description

2-Methoxy-5-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a methoxy and a trifluoromethyl group on the phenylacetic acid core, makes it a versatile intermediate for creating compounds with tailored electronic and steric properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where the introduction of fluorine atoms can dramatically alter a molecule's metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) agents, anti-inflammatory drugs, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in display technologies, leveraging its aromatic and polar characteristics.
• Organic Electronic Materials: Employed in the synthesis of monomers and polymers for organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Material Research: Acts as a specialty monomer or cross-linking agent in the development of high-performance polymers and coatings.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination chemistry or coupling reactions in academic and industrial labs.

Basic Information

Product Name	2-Methoxy-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1000523-82-9
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	[2-Methoxy-5-(trifluoromethyl)phenyl]acetic acid; α-(2-Methoxy-5-(trifluoromethyl)phenyl)acetic Acid; 2-(2-Methoxy-5-(trifluoromethyl)phenyl)acetic Acid; 2-Methoxy-5-trifluoromethylphenylacetic Acid; (2-Methoxy-5-(trifluoromethyl)phenyl)ethanoic acid; 5-Trifluoromethyl-2-methoxyphenylacetic Acid
EINECS	Contact for details

Quality Control

Our 2-Methoxy-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.