Description

2-(2-Chloro-3-Fluorophenyl)Acetic Acid is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated phenylacetic acid motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the chloro-fluoro substitution pattern enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport materials and host matrices for efficient OLED devices.
• Chemical Research & Development: A versatile building block for academic and industrial R&D in organofluorine chemistry and cross-coupling reactions.
• Specialty Polymer Modifier: Can be incorporated to impart specific properties, such as altered solubility or thermal stability, into specialty polymer chains.

Basic Information

Product Name	2-(2-Chloro-3-Fluorophenyl)Acetic Acid
CAS No.	1000523-07-8
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	(2-Chloro-3-fluorophenyl)acetic acid; 2-Chloro-3-fluorobenzeneacetic acid; α-(2-Chloro-3-fluorophenyl)acetic acid; 2-(2-Chloro-3-fluorophenyl)ethanoic acid; o-Chloro-m-fluorophenylacetic acid; 2-Chloro-3-fluoro-α-toluic acid; 2-Chloro-3-fluorobenzylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-3-Fluorophenyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as an organic acid, appropriate chemical storage cabinets are recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.