Description

2-Chloro-4-Fluoro-5-Methylphenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated phenylacetic acid moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with specific electronic or structural properties.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Methylphenylacetic Acid
CAS No.	1000522-29-1
Molecular Formula	C9H8ClFO2
Molecular Weight	202.61 g/mol
Synonyms	(2-Chloro-4-fluoro-5-methylphenyl)acetic acid; 2-Chloro-4-fluoro-5-methylbenzeneacetic acid; α-(2-Chloro-4-fluoro-5-methylphenyl)acetic acid; 2-(2-Chloro-4-fluoro-5-methylphenyl)acetic acid; 1000522-29-1; 5-Methyl-2-chloro-4-fluorophenylacetic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Methylphenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.