Description

2-Methyl-5-(Trifluoromethyl)Phenylacetic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group imparts desirable metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate this specific fluorinated motif into novel molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Advanced Polymer Modifiers: Incorporated into specialty polymers to alter surface properties, chemical resistance, and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorination chemistry and reaction pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	1000517-01-0
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	[2-Methyl-5-(trifluoromethyl)phenyl]acetic acid; α-(2-Methyl-5-(trifluoromethyl)phenyl)acetic acid; 2-(2-Methyl-5-(trifluoromethyl)phenyl)acetic acid; 5-(Trifluoromethyl)-o-tolylacetic acid; 2-Methyl-5-trifluoromethylphenylacetic acid; 2-Methyl-5-(trifluoromethyl)benzenacetic acid; (2-Methyl-5-(trifluoromethyl)phenyl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with stringent industry standards. Certificates of Analysis (COA) documenting full specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.