Description

Sinomenine n-Oxide is a key alkaloid derivative and oxidative metabolite of the natural compound Sinomenine. This specialized intermediate is of significant interest for its role in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis of novel compounds and in-depth pharmacological studies.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies, pharmacokinetics, and drug metabolism research.
• Biochemical Research: Employed in studies investigating anti-inflammatory and immunomodulatory pathways and mechanisms.
• Academic & Contract Research: Serves as a high-purity reagent for universities and CROs (Contract Research Organizations) conducting pharmacological screenings.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of Sinomenine-related compounds.
• Quality Control & Method Development: Acts as a reference material for HPLC, LC-MS, and other analytical method development and validation in QC laboratories.

Basic Information

Product Name	Sinomenine n-Oxide
CAS No.	1000026-77-6
Molecular Formula	C19H23NO5
Molecular Weight	345.39 g/mol
Synonyms	Sinomenine N-Oxide; 7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-9α,13α,14α-morphinan-6-one 17-Oxide; Sinomenine Oxide; Sinomenine N-Oxide Alkaloid; (9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one 17-Oxide
EINECS	Contact for details

Quality Control

Our Sinomenine n-Oxide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.