Description

1,4-Diazabicyclo[2.2.2]octan-2-one,3,3,5,5-tetramethyl-(9Ci) is a specialized bicyclic organic compound featuring a unique diazabicyclooctane (DABCO) core structure with carbonyl and tetramethyl substitutions. This compound matters as a high-value chemical intermediate and ligand, prized for its steric and electronic properties which are critical in advanced organic synthesis and catalysis. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications ranging from asymmetric synthesis to the development of novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those requiring rigid, nitrogen-containing heterocycles.
• Catalyst & Ligand Precursor: Used in the development and preparation of organocatalysts and transition metal ligands for asymmetric hydrogenation and cross-coupling reactions.
• Agrochemical Synthesis: Employed in the research and production of novel herbicides, fungicides, and insecticides where its structural motif can enhance biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic frameworks.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, enabling new synthetic pathways.

Basic Information

Product Name	1,4-Diazabicyclo[2.2.2]octan-2-one,3,3,5,5-tetramethyl-(9Ci)
CAS No.	199926-45-9
Molecular Formula	C10H18N2O
Molecular Weight	182.26 g/mol
Synonyms	3,3,5,5-Tetramethyl-1,4-diazabicyclo[2.2.2]octan-2-one; 3,3,5,5-Tetramethyl-DABCO-2-one; Tetramethyl DABCO lactam; 1,4-Diazabicyclo[2.2.2]octan-2-one, 3,3,5,5-tetramethyl-; 3,3,5,5-Tetramethyl-2-oxo-1,4-diazabicyclo[2.2.2]octane; DABCO lactam derivative; 199926-45-9 (CAS)
EINECS	Contact for details

Quality Control

Our 1,4-Diazabicyclo[2.2.2]octan-2-one,3,3,5,5-tetramethyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.