Description

Z-Orn(Boc)-Oh is a protected amino acid derivative, specifically Nα-Boc-ornithine, which serves as a crucial building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptides with specific sequences and modifications. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of novel therapeutic peptides and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of ornithine residues into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling strategies for constructing peptide fragments.
• Bioconjugation and Linker Chemistry: The side-chain amine (protected as Boc) and carboxylic acid group provide handles for creating custom linkers or attaching payloads.
• Research of Polyamine Analogues: Serves as a precursor in the study of compounds related to cellular growth and proliferation.
• Production of Custom Amino Acids: Used as a starting material for the synthesis of specialized or non-proteinogenic amino acid derivatives.
• Pharmaceutical Intermediate: A critical raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.

Basic Information

Product Name	Z-Orn(Boc)-Oh
CAS No.	199924-46-4
Molecular Formula	C₁₇H₂₄N₂O₆
Molecular Weight	352.38 g/mol
Synonyms	Nα-Z-Nδ-Boc-L-Ornithine; Z-Orn(Boc)-OH; Nα-Carbobenzoxy-Nδ-tert-butoxycarbonyl-L-ornithine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-((tert-butoxycarbonyl)amino)pentanoic acid; Fmoc-Orn(Boc)-OH; Boc-Orn(Z)-OH; Nδ-Boc-Nα-Z-L-ornithine; Nα-(Benzyloxycarbonyl)-Nδ-(tert-butoxycarbonyl)-L-ornithine
EINECS	Contact for details

Quality Control

Our Z-Orn(Boc)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.