Description

Recombinant Human Soluble P55 Tumour Necrosis Factor Receptor is a high-purity, biologically active protein produced using recombinant DNA technology. This product is critical for research and development in immunology and autoimmune disease studies, as it acts as a decoy receptor to bind and neutralize Tumor Necrosis Factor-alpha (TNF-α). It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotech companies for assay development, drug discovery, and as a critical reference standard.

Application

• Biopharmaceutical Research & Development: Used as a key reagent in the study of TNF-α signaling pathways and inflammatory diseases.
• Drug Discovery & Screening: Serves as a target or competitor in high-throughput screening (HTS) assays for novel anti-inflammatory therapeutics.
• Assay Development & Validation: Employed as a critical standard and control in ELISA, cell-based bioassays, and other diagnostic test systems.
• Academic & Clinical Research: Facilitates fundamental research into autoimmune disorders such as rheumatoid arthritis, Crohn's disease, and psoriasis.
• Quality Control in Biologics Manufacturing: Acts as a reference material for the potency testing and lot release of TNF-α inhibitor drugs.

Basic Information

Product Name	Recombinant Human Soluble P55 Tumour Necrosis Factor Receptor
CAS No.	199685-57-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	sTNFR-I; sTNF R1; Soluble TNF Receptor Type I; TNFRSF1A; CD120a; p55; Recombinant Human TNF R1; Tumor Necrosis Factor Receptor Superfamily Member 1A; TNF-α Receptor I
EINECS	Contact for details

Quality Control

Our Recombinant Human Soluble P55 Tumour Necrosis Factor Receptor is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, HPLC for purity assessment, endotoxin testing (LAL), and functional bioactivity assays. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Upon reconstitution, aliquot and store at -80°C to avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use and equilibrated to room temperature before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Endotoxin Level (LAL)	< 1.0 EU/μg
Biological Activity (Cell-based assay)	Contact for details
Protein Content (BCA)	Contact for details
Solubility	Soluble in sterile PBS or cell culture grade water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.