Description

Kinase (Phosphorylating), Gene Rac Protein Kinase (Human) is a highly specific recombinant enzyme critical for signal transduction research. This product is essential for studying cell proliferation, cytoskeletal reorganization, and oncogenic pathways mediated by the Rac subfamily of Rho GTPases. It is primarily utilized by pharmaceutical R&D teams, academic research laboratories, and diagnostic developers focused on cancer biology, neuroscience, and inflammatory diseases.

Application

• Biochemical Research & Assay Development: Used as a key reagent in in vitro kinase assays to study phosphorylation kinetics, substrate specificity, and inhibitor screening.
• Drug Discovery & High-Throughput Screening (HTS): Serves as a target enzyme for identifying and validating novel small-molecule inhibitors for therapeutic intervention.
• Cell Signaling Pathway Analysis: Employed to phosphorylate downstream effector proteins, enabling the study of Rac1-mediated signaling networks in cancer and neurological disorders.
• Diagnostic Kit Manufacturing: Integrated as a core component in ELISA-based kits and other diagnostic platforms for detecting kinase activity or related biomarkers.
• Academic & Institutional Research: Supports fundamental research in molecular biology, cellular physiology, and disease mechanism studies.
• Protein-Protein Interaction Studies: Used to investigate the functional consequences of phosphorylation on binding partners and complex formation.

Basic Information

Product Name	Kinase (Phosphorylating), Gene Rac Protein Kinase (Human)
CAS No.	199489-89-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rac Protein Kinase; p21-Rac1 Protein Kinase; Recombinant Human Rac Kinase; Rac-PK; Protein Kinase Rac; EC 2.7.11.1 (associated with kinase activity); Rac1-Activated Kinase; Phosphorylating Kinase for Rac substrates
EINECS	Contact for details

Quality Control

Our recombinant kinase products are manufactured under stringent quality systems. Each batch is subjected to rigorous purity and activity testing, including SDS-PAGE for molecular weight verification, HPLC for purity assessment, and functional activity assays to ensure specific enzymatic performance. Certificates of Analysis (COA) detailing lot-specific data are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. Aliquot upon receipt for optimal preservation of enzymatic activity.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Purity (SDS-PAGE)	≥ 90%
Specific Activity	≥ XX units/mg (Lot-specific)
Protein Concentration	XX µg/µL (Lot-specific)
Buffer Composition	XX mM Tris-HCl, XX mM NaCl, XX% Glycerol, pH X.X
Endotoxin Level	< 1.0 EU/µg
Identification (Western Blot)	Positive

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.