Description

1,2-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Ethane is a specialized, high-value organophosphorus ligand with a rigid, electron-deficient structure. This compound matters for its exceptional ability to facilitate challenging cross-coupling and hydrogenation reactions in the presence of sensitive functional groups. It is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and high-performance polymers.

Application

• Catalyst Ligand for C-C & C-X Cross-Coupling: Essential for demanding Suzuki-Miyaura, Buchwald-Hartwig, and Negishi reactions, especially with sterically hindered or deactivated substrates.
• Asymmetric Hydrogenation Catalysis: Used in the synthesis of chiral intermediates for active pharmaceutical ingredients (APIs) and fine chemicals.
• Pharmaceutical Intermediate Synthesis: Enables key steps in the production of complex drug molecules, including those with fluorinated motifs.
• Agrochemical Active Ingredient Development: Facilitates the creation of novel herbicides, fungicides, and insecticides with improved efficacy.
• Advanced Material & Polymer Chemistry: Employed in the synthesis of specialty monomers and fluorinated polymers with unique properties.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new catalytic transformations in both university and corporate research labs.

Basic Information

Product Name	1,2-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Ethane
CAS No.	199342-62-6
Molecular Formula	C34H16F24P2
Molecular Weight	870.42 g/mol
Synonyms	DTFMPE; 1,2-Ethanediylbis[bis[3,5-bis(trifluoromethyl)phenyl]phosphine]; Bis[3,5-bis(trifluoromethyl)phenyl][2-[bis[3,5-bis(trifluoromethyl)phenyl]phosphino]ethyl]phosphine; DTFMPE Ligand; 3,5-Bis(trifluoromethyl)phenyl-based Diphosphine Ligand; Electron-Deficient Diphosphine Ligand; Fluorinated Bidentate Phosphine Ligand
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Bis[Bis(3,5-Ditrifluoromethylphenyl)Phosphino]Ethane is synthesized and handled under strict inert atmosphere conditions to ensure integrity. We employ advanced analytical techniques, including NMR (1H, 13C, 31P), HPLC, and elemental analysis, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee consistency and support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. Due to its hygroscopic and easily oxidized nature, the container should only be opened in a controlled, moisture-free environment and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR Purity	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.