Description

H-Asp(Obzl)-Nh2 Hcl is a protected aspartic acid derivative, specifically the benzyl ester hydrochloride salt of aspartamide. This compound is a crucial building block in the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the controlled incorporation of aspartic acid into peptide chains.
• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation Chemistry: Used to introduce specific functional handles or linkers onto biomolecules for targeted drug delivery systems.
• Biochemical Research: Employed in studying enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Combinatorial Library Synthesis: A valuable component for generating diverse libraries of peptide compounds for high-throughput screening.
• Material Science: Potential use in the synthesis of specialized polymers and biomaterials with tailored properties.

Basic Information

Product Name	H-Asp(Obzl)-Nh2 Hcl
CAS No.	199118-68-8
Molecular Formula	C11H15ClN2O3
Molecular Weight	258.70 g/mol
Synonyms	L-Aspartic acid, N-benzyl ester, amide, hydrochloride; Aspartic acid β-benzyl ester amide hydrochloride; H-Asp-OBzl-NH2·HCl; Fmoc-Asp(OBzl)-OH; (S)-2-Amino-3-(benzyloxycarbonyl)propionamide hydrochloride; Aspartamide benzyl ester hydrochloride; Boc-Asp(OBzl)-OH; Benzyl L-aspartate amide hydrochloride
EINECS	Contact for details

Quality Control

Our H-Asp(Obzl)-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.