Description

Fmoc-L-4-Methylphe CAS NO 199006-54-7 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block, enabling the controlled and efficient assembly of complex peptide sequences for research and therapeutic development. It is primarily required by pharmaceutical R&D laboratories, biotechnology companies, and CROs engaged in the discovery and production of novel peptide-based drugs and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Fmoc-protected amino acid for the automated or manual synthesis of custom peptides.
• Pharmaceutical Research: Used in the discovery and development of peptide therapeutics, hormones, and enzyme inhibitors.
• Bioconjugation: Acts as a key intermediate for creating peptide-protein or peptide-small molecule conjugates.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive compounds.
• Proteomics & Biochemical Studies: Utilized to synthesize peptide antigens, substrates, or standards for analytical and functional assays.
• Material Science: Incorporated into peptide-based biomaterials and hydrogels for specialized applications.

Basic Information

Product Name	Fmoc-L-4-Methylphe
CAS No.	199006-54-7
Molecular Formula	C25H23NO4
Molecular Weight	401.46 g/mol
Synonyms	Fmoc-4-methyl-L-phenylalanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-4-methyl-L-phenylalanine; Fmoc-4-Me-Phe-OH; Fmoc-L-4-methylphenylalanine; N-Fmoc-4-methyl-L-phenylalanine; (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-(4-methylphenyl)propanoic acid; Fmoc-Phe(4-Me)-OH; Fmoc-L-(4-methyl)Phe
EINECS	Contact for details

Quality Control

Our Fmoc-L-4-Methylphe is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive peptide synthesis applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral integrity, and impurity profiles. We adhere to relevant industry standards for fine chemicals used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Optical Rotation	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.