Description

2,4-Difluoro-n-Methoxy-n-Methylbenzamide is a high-purity fluorinated benzamide derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular architecture, which incorporates strategically placed fluorine atoms and methoxy/methylamide functionalities to modulate reactivity and physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to construct complex molecules for new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluoro motif enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored electronic and optical properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, amide bond formations, and as a scaffold for constructing diverse heterocyclic compounds in medicinal chemistry.
• Fluorine Chemistry Studies: A valuable substrate for investigating the influence of fluorine substitution patterns on molecular conformation and intermolecular interactions.

Basic Information

Product Name	2,4-Difluoro-n-Methoxy-n-Methylbenzamide
CAS No.	198967-25-8
Molecular Formula	C10H11F2NO2
Molecular Weight	215.20 g/mol
Synonyms	N-Methoxy-N,2,4-trifluorobenzamide; 2,4-Difluoro-N-methoxy-N-methylbenzamide; Benzamide, 2,4-difluoro-N-methoxy-N-methyl-; N-Methoxy-N-methyl-2,4-difluorobenzamide; 198967-25-8; 2,4-Difluoro-N-(methoxy)-N-methylbenzamide
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-n-Methoxy-n-Methylbenzamide is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.