Description

(R)-3-Hydroxypentanenitrile CAS NO 198561-27-2 is a chiral, enantiomerically pure nitrile derivative that serves as a critical intermediate in advanced organic synthesis. Its value lies in the stereogenic center and bifunctional nature, enabling the construction of complex molecules with high optical purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiomerically pure drugs, including β-blockers, antidepressants, and antiviral agents.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and auxiliaries used in metal-catalyzed asymmetric reactions.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical control.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and stereoselective synthesis research.

Basic Information

Product Name	(R)-3-Hydroxypentanenitrile
CAS No.	198561-27-2
Molecular Formula	C5H9NO
Molecular Weight	99.13 g/mol
Synonyms	(R)-3-Hydroxyvaleronitrile; (R)-3-Hydroxypentanenitrile; (3R)-3-Hydroxypentanenitrile; (R)-3-Hydroxybutyronitrile, Ethyl-; (R)-3-Hydroxy pentanenitrile; D-3-Hydroxypentanenitrile; (R)-3-Hydroxy pentanenitrile; (R)-3-Hydroxyvaleronitrile
EINECS	Contact for details

Quality Control

Our (R)-3-Hydroxypentanenitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.