Description

(2R)-2-Cyclohexyl-2-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Acetic Acid is a high-purity chiral building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in protease inhibitor and peptide mimetic drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific herbicides, fungicides, and insecticides where specific chirality enhances efficacy and reduces environmental impact.
• Peptidomimetics & Bioactive Molecules: Serves as a constrained amino acid analog for designing and synthesizing peptidomimetics and other bioactive compounds with improved metabolic stability.
• Asymmetric Catalysis Ligand Precursor: Can be utilized in the development of novel chiral ligands and catalysts for asymmetric synthesis applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for exploring new synthetic routes in fine chemical production.

Basic Information

Product Name	(2R)-2-Cyclohexyl-2-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Acetic Acid
CAS No.	198470-08-5
Molecular Formula	C₁₄H₂₅NO₄
Molecular Weight	271.35 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-2-cyclohexylacetic acid; Boc-(R)-Cyclohexylglycine; (R)-Boc-Cyclohexylglycine; (R)-2-(Boc-amino)-2-cyclohexylacetic acid; (2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-2-cyclohexylacetic acid; (R)-N-Boc-2-amino-2-cyclohexylacetic acid; N-(tert-Butoxycarbonyl)-D-cyclohexylglycine
EINECS	Contact for details

Quality Control

Our (2R)-2-Cyclohexyl-2-[(2-Methylpropan-2-Yl)Oxycarbonylamino]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.