Description

Amylin (1-13) (Human) is a synthetic peptide fragment corresponding to the first 13 amino acids of the human amylin hormone. This compound is a critical research tool for studying the structure, function, and aggregation behavior of the full-length amylin peptide, which is implicated in type 2 diabetes. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic disease research and peptide-based drug discovery.

Application

• Biochemical Research: Used as a reference standard and model compound for studying the aggregation kinetics and amyloid formation of human amylin (IAPP).
• Drug Discovery Screening: Serves as a key reagent in high-throughput assays to identify potential inhibitors of amylin aggregation for therapeutic development in diabetes.
• Structure-Activity Relationship (SAR) Studies: Enables researchers to investigate the contribution of the N-terminal region to the biological activity and toxicity of the full-length hormone.
• Antibody Development & Immunoassays: Acts as an antigen for the production and characterization of antibodies specific to the amylin peptide sequence.
• Peptide Chemistry & Conjugation: Provides a well-defined peptide fragment for conjugation chemistry, labeling studies, or the synthesis of larger peptide constructs.
• Academic & Educational Use: Employed in university laboratories for teaching advanced concepts in peptide chemistry, protein misfolding, and endocrinology.

Basic Information

Product Name	Amylin (1-13) (Human)
CAS No.	198328-30-2
Molecular Formula	C66H103N19O19S2
Molecular Weight	1490.8 g/mol
Synonyms	Human Amylin (1-13); IAPP (1-13); Islet Amyloid Polypeptide Fragment 1-13; H-IAPP(1-13); KCNTATCATQRLN-NH2 (disulfide bridge: Cys2-Cys7); Amylin 1-13 amide, human; CAS 198328-30-2
EINECS	Contact for details

Quality Control

Our Amylin (1-13) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring the material meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.