Description

(2-Bromo-5-Methoxy-3-Methyl-Phenyl)-Acetonitrile is a versatile and high-purity organic building block, essential for advanced chemical synthesis. Its unique bromo-methoxy-methyl substituted benzonitrile structure makes it a critical intermediate for constructing complex molecules with high precision. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its halogen and nitrile functionality.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for organic electronic materials, such as OLED and OFET components, due to its electron-withdrawing nitrile group and aromatic system.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs serving the life sciences sector.
• Academic and R&D Laboratories: Employed in methodological chemistry research for cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	(2-Bromo-5-Methoxy-3-Methyl-Phenyl)-Acetonitrile
CAS No.	198274-48-5
Molecular Formula	C10H10BrNO
Molecular Weight	240.10 g/mol
Synonyms	2-(2-Bromo-5-methoxy-3-methylphenyl)acetonitrile; (2-Bromo-5-methoxy-3-methylphenyl)acetonitrile; 2-Bromo-5-methoxy-3-methylbenzyl cyanide; α-Cyano-2-bromo-5-methoxy-3-methyltoluene; 198274-48-5; 2-Bromo-5-methoxy-3-methylbenzenacetonitrile; 3-Methyl-2-bromo-5-methoxyphenylacetonitrile
EINECS	Contact for details

Quality Control

Every batch of (2-Bromo-5-Methoxy-3-Methyl-Phenyl)-Acetonitrile is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to ensure compliance with your research and development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.