Description

1,3A,5,7B-Tetrakis(Trifluoromethyl)-2-Phospha-6-Oxa-9-Oxabicyclo[3.3.1]-Nonane-3B,7A-Diol is a highly fluorinated, phosphorus-containing bicyclic compound with a complex, rigid molecular architecture. This specialized organophosphorus derivative is valued for its unique electronic properties and structural stability, making it a critical advanced intermediate in sophisticated chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients, as well as by material scientists exploring high-performance polymers and specialty catalysts.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel drug candidates, particularly those requiring fluorinated or phosphorus-based pharmacophores to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where its fluorinated structure can contribute to improved efficacy and environmental profile.
• Ligand for Catalysis: Acts as a precursor for creating specialized ligands in transition metal catalysis, useful in asymmetric synthesis and cross-coupling reactions.
• Advanced Material Research: Investigated as a monomer or additive for high-performance polymers, coatings, and electronic materials where thermal stability and specific dielectric properties are required.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the synthesis and reactivity of polyfluorinated organophosphorus molecules.

Basic Information

Product Name	1,3A,5,7B-Tetrakis(Trifluoromethyl)-2-Phospha-6-Oxa-9-Oxabicyclo[3.3.1]-Nonane-3B,7A-Diol
CAS No.	197787-23-8
Molecular Formula	C10H4F12O4P
Molecular Weight	456.10 g/mol
Synonyms	2-Phospha-6-oxa-9-oxabicyclo[3.3.1]nonane-3b,7a-diol, 1,3a,5,7b-tetrakis(trifluoromethyl)-; P-Hydroxy Tetrakis(trifluoromethyl) Bicyclic Phosphite Diol; Fluorinated Bicyclic Phosphorus Diol; 197787-23-8; Advanced Fluorophosphonate Intermediate; Polyfluorinated Organophosphorus Compound; Bicyclic Phosphite Ester Diol Derivative
EINECS	Contact for details

Quality Control

Our production of 1,3A,5,7B-Tetrakis(Trifluoromethyl)-2-Phospha-6-Oxa-9-Oxabicyclo[3.3.1]-Nonane-3B,7A-Diol adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We maintain traceability and documentation in line with cGMP principles for advanced pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.