Description

n-Me-Ser(Tbu)-Oh is a protected serine derivative, specifically N-methyl-O-tert-butyl-serine, widely used as a key building block in peptide synthesis. This compound is crucial for introducing modified serine residues, enabling the creation of peptides with enhanced stability, bioavailability, and specific biological activity. It is an essential raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries developing novel therapeutic peptides and protein-based products.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled incorporation of N-methylated serine residues into peptide chains.
• Pharmaceutical Intermediate: Used in the research and development of peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Peptidomimetic Design: Serves as a precursor for creating stable peptide mimics that resist enzymatic degradation, improving drug half-life.
• Bioconjugation and Labeling: The reactive functional groups allow for site-specific modification and labeling of peptides for diagnostic or research purposes.
• Agrochemical Research: Employed in the synthesis of bioactive peptides for crop protection and growth regulation.
• Academic & Industrial R&D: A standard reagent in laboratories focused on organic chemistry, medicinal chemistry, and chemical biology.

Basic Information

Product Name	n-Me-Ser(Tbu)-Oh
CAS No.	197632-83-0
Molecular Formula	C8H17NO3
Molecular Weight	175.23 g/mol
Synonyms	N-Methyl-O-tert-butyl-L-serine; (S)-2-(Methylamino)-3-((tert-butoxy)oxy)propanoic acid; O-tert-Butyl-N-methylserine; N-Methylserine O-tert-butyl ether; Fmoc-N-Me-Ser(tBu)-OH (precursor); Boc-N-Me-Ser(tBu)-OH (precursor); Protected N-methylserine; CAS 197632-83-0
EINECS	Contact for details

Quality Control

Our n-Me-Ser(Tbu)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via NMR and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade requirements for advanced synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.