Description

Fmoc-2-Aminooctanoic Acid CAS NO 197384-29-5 is a high-purity, protected amino acid derivative essential for solid-phase peptide synthesis (SPPS). This compound serves as a critical building block for the controlled introduction of non-natural, hydrophobic amino acid residues into peptide chains, enabling the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research laboratories focused on peptide-based drug discovery, therapeutic agent development, and biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the incorporation of 2-aminooctanoic acid, a non-proteinogenic amino acid, into custom peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide therapeutics, including antimicrobial peptides (AMPs), hormone analogs, and targeted drug delivery systems.
• Combinatorial Chemistry Libraries: Serves as a valuable component for creating diverse peptide libraries to screen for new biological activity and drug leads.
• Bioconjugation & Protein Engineering: Facilitates the site-specific modification of peptides and proteins for labeling, imaging, or enhancing pharmacokinetic properties.
• Academic & Biochemical Research: Employed in studies investigating protein structure-function relationships, enzyme substrates, and receptor-ligand interactions.
• Material Science: Potential use in the synthesis of peptide-based biomaterials and functional polymers.

Basic Information

Product Name	Fmoc-2-Aminooctanoic Acid
CAS No.	197384-29-5
Molecular Formula	C₂₃H₂₇NO₄
Molecular Weight	381.47 g/mol
Synonyms	Fmoc-2-AOC-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-aminooctanoic Acid; (R/S)-2-[(9-Fluorenylmethoxycarbonyl)amino]octanoic Acid; Fmoc-Amino(2)octanoic Acid; Fmoc-2-Amino-n-octanoic Acid; N-Fmoc-2-aminooctanoic acid; 2-(Fmoc-amino)octanoic acid; Fmoc-DL-2-Aminooctanoic Acid
EINECS	Contact for details

Quality Control

Our Fmoc-2-Aminooctanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements of advanced research and development. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.