Description

D-Threonine, n-Acetyl- (9Ci) is a specific, high-purity derivative of the amino acid threonine, characterized by its D-configuration and N-acetyl functional group. This compound is a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of pharmaceuticals and bioactive peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require enantiomerically pure components for drug discovery, process development, and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), especially for drugs targeting specific biological pathways.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to construct peptides with defined stereochemistry.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies, metabolic pathway analysis, and as a substrate for acylase enzymes.
• Asymmetric Catalysis: Employed as a ligand or precursor for catalysts in asymmetric synthesis to induce chirality in target molecules.
• Nutritional Science Research: Used in studies investigating the metabolism and function of D-amino acids and their derivatives.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, LC-MS).

Basic Information

Product Name	D-Threonine, n-Acetyl- (9Ci)
CAS No.	197302-88-8
Molecular Formula	C6H11NO4
Molecular Weight	161.16 g/mol
Synonyms	N-Acetyl-D-threonine; (2R,3S)-2-Acetamido-3-hydroxybutanoic acid; D-α-Acetamido-β-hydroxybutyric acid; Ac-D-Thr-OH; N-Acetyl-D-threonine; D-Thr(Ac)-OH; (2R,3S)-N-Acetylthreonine
EINECS	Contact for details

Quality Control

Our D-Threonine, n-Acetyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality, identity, and purity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% de (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.