Description

L-Leucinamide, n-[(Phenylmethoxy)Carbonyl]-β-Alanyl- is a protected peptide building block, specifically a dipeptide derivative, used in solid-phase peptide synthesis (SPPS). Its value lies in enabling the controlled, sequential assembly of complex peptides and proteins by providing a specific amino acid sequence with orthogonal protecting groups. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating therapeutic peptides, and in biochemical research for studying protein structure and function.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic peptides and peptidomimetics for drug discovery and development.
• Solid-Phase Peptide Synthesis (SPPS): Used in Fmoc/t-Bu chemistry for the controlled, sequential addition of amino acids to construct target peptide sequences.
• Biochemical Research: Employed in academic and industrial laboratories to study peptide-protein interactions, enzyme substrates, and hormone analogs.
• API (Active Pharmaceutical Ingredient) Development: Serves as a critical intermediate in the multi-step synthesis of complex peptide-based active ingredients.
• Combinatorial Chemistry: Utilized in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Proteomics and Biomarker Research: Acts as a standard or reagent in the synthesis of labeled peptides for mass spectrometry and diagnostic assays.

Basic Information

Item	Details
Product Name	L-Leucinamide, n-[(Phenylmethoxy)Carbonyl]-β-Alanyl-
CAS No.	197237-13-1
Molecular Formula	C21H31N3O5
Molecular Weight	405.49 g/mol
Synonyms	Fmoc-β-Ala-Leu-NH2; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-β-alanyl-L-leucinamide; Fmoc-β-Ala-L-Leu-NH2; (9-Fluorenylmethoxycarbonyl)-β-alanyl-L-leucinamide; Fmoc-β-alanyl-L-leucinamide; N-Fmoc-β-alanyl-L-leucinamide; Fmoc-βAla-Leu-NH2; Peptide Synthesis Building Block Fmoc-β-Ala-Leu-NH2
EINECS	Contact for details

Quality Control

Our L-Leucinamide, n-[(Phenylmethoxy)Carbonyl]-β-Alanyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure compliance with your research or cGMP-grade requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 5.0 %
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.