Description

1,2,2-Trimethyl-3-p-Tolylcarbamoyl-Cyclopentanecarboxylic Acid is a specialized organic compound featuring a cyclopentane core substituted with carboxylic acid and p-tolylcarbamoyl groups. This structure makes it a valuable advanced pharmaceutical intermediate (API) and a versatile building block for fine chemical synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory applications.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides and fungicides with targeted modes of action.
• Fine Chemical Building Block: Used in organic synthesis to construct complex molecular architectures for material science and specialty chemistry.
• Research & Development: Essential for medicinal chemistry programs exploring structure-activity relationships (SAR) in new therapeutic areas.
• Chiral Auxiliary/Resolving Agent: Potential use in asymmetric synthesis due to its defined stereochemistry for enantioselective reactions.

Basic Information

Product Name	1,2,2-Trimethyl-3-p-Tolylcarbamoyl-Cyclopentanecarboxylic Acid
CAS No.	197236-38-7
Molecular Formula	C18H25NO3
Molecular Weight	303.40 g/mol
Synonyms	3-[(4-Methylphenyl)carbamoyl]-1,2,2-trimethylcyclopentane-1-carboxylic acid; 1,2,2-Trimethyl-3-[(4-methylphenyl)aminocarbonyl]cyclopentanecarboxylic Acid; 1-Cyclopentanecarboxylic acid, 3-[[(4-methylphenyl)amino]carbonyl]-1,2,2-trimethyl-; p-Tolylcarbamoyl substituted trimethylcyclopentanecarboxylic acid; TTC Acid (abbrev.); Advanced Intermediate 197236-38-7.
EINECS	Contact for details

Quality Control

Our production of 1,2,2-Trimethyl-3-p-Tolylcarbamoyl-Cyclopentanecarboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting research-grade and GMP-grade specifications. A detailed Certificate of Analysis (COA) providing batch-specific data for identity, purity, and impurities is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.