Description

1,3A-Methano-3Ah-Indene-8-Carbonitrile,Octahydro-4-Oxo-,(1-α-,3A-α-,7A-Bta-,8S*)-(9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex, polycyclic molecular structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated chiral building blocks. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses. Our supply is backed by stringent quality control to ensure batch-to-batch consistency for your critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new Active Pharmaceutical Ingredients (APIs).
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses, particularly in constructing fused ring systems.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Asymmetric Synthesis: Utilized in reactions requiring specific stereochemistry due to its defined chiral centers.
• Process Chemistry Development: Acts as a starting material or intermediate in developing scalable manufacturing routes for target molecules.

Basic Information

Product Name	1,3A-Methano-3Ah-Indene-8-Carbonitrile,Octahydro-4-Oxo-,(1-α-,3A-α-,7A-Bta-,8S*)-(9Ci)
CAS No.	196790-65-5
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	Octahydro-4-oxo-1,3a-methano-3aH-indene-8-carbonitrile; (1α,3aα,7aβ,8S*)-Octahydro-4-oxo-1,3a-methano-3aH-indene-8-carbonitrile; 1,3a-Methano-3aH-indene-8-carbonitrile, octahydro-4-oxo-, (1α,3aα,7aβ,8S*)-; 196790-65-5; Advanced Pharmaceutical Intermediate; Chiral Nitrile Building Block; Polycyclic Nitrile Synthon.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is analyzed using modern analytical techniques including HPLC, GC, and NMR to confirm identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.