Description

(R)-2-Acetylamino-3-Methoxy-Propionic Acid CAS NO 196601-67-9 is a high-purity, non-natural amino acid derivative characterized by its chiral (R)-configuration and methoxy side chain. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals and bioactive molecules, where stereochemical purity is paramount. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of novel therapeutic agents, peptide mimetics, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological disorders.
• Peptidomimetics & Constrained Peptides: Serves as a building block for designing peptide analogs with enhanced metabolic stability and bioavailability.
• Protease Inhibitor Synthesis: Used in the construction of inhibitor scaffolds targeting specific protease enzymes.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal complexation.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to investigate reaction mechanisms and selectivity.
• Material Science: A potential monomer for creating specialized polymers with unique chiral or hydrophilic properties.

Basic Information

Product Name	(R)-2-Acetylamino-3-Methoxy-Propionic Acid
CAS No.	196601-67-9
Molecular Formula	C6H11NO5
Molecular Weight	177.16 g/mol
Synonyms	(R)-2-Acetamido-3-methoxypropanoic acid; (R)-N-Acetyl-3-methoxyalanine; (2R)-2-Acetamido-3-methoxypropanoic acid; (R)-3-Methoxy-N-acetylalanine; N-Acetyl-O-methyl-D-serine; D-3-Methoxy-N-acetylalanine; N-Acetyl-3-methoxy-D-alanine; Ac-Met(O)-OH
EINECS	Contact for details

Quality Control

Our (R)-2-Acetylamino-3-Methoxy-Propionic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess determination, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.