Description

5-Bromo-4,4,5,5-tetrafluoropent-2-en-1-ol is a high-value fluorinated organic building block characterized by a reactive bromine atom, a tetrafluoroalkyl chain, and an alcohol functional group. This unique molecular architecture makes it a critical intermediate for synthesizing advanced materials and pharmaceuticals, where the introduction of fluorine atoms is essential for modulating properties like metabolic stability, lipophilicity, and chemical resistance. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and pesticides, where fluorine incorporation improves environmental stability and efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and thermal stability.
• Polymer & Resin Modification: Employed to introduce fluorine into polymer backbones or side chains, enhancing properties such as chemical resistance, weatherability, and surface energy.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck), enabling the construction of complex carbon frameworks.
• Fluorinated Surfactant & Coating Additives: Acts as a building block for surface-active agents and additives that require specific hydrophobic and oleophobic characteristics.

Basic Information

Product Name	5-Bromo-4,4,5,5-tetrafluoropent-2-en-1-ol
CAS No.	196597-11-2
Molecular Formula	C5H5BrF4O
Molecular Weight	237.00 g/mol
Synonyms	5-Bromo-4,4,5,5-tetrafluoro-2-penten-1-ol; 2-Penten-1-ol, 5-bromo-4,4,5,5-tetrafluoro-; 4,4,5,5-Tetrafluoro-5-bromopent-2-en-1-ol; (E/Z)-5-Bromo-4,4,5,5-tetrafluoropent-2-en-1-ol; Bromotetrafluoropentenol; Fluorinated bromoalkenol intermediate
EINECS	Contact for details

Quality Control

Our 5-Bromo-4,4,5,5-tetrafluoropent-2-en-1-ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Isomer Ratio (GC/HPLC)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.