Description

1-Boc-2-Methoxypiperidine is a high-purity, protected piperidine derivative widely used as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the piperidine scaffold imparts specific biological activity.
• Peptidomimetics Research: Serves as a constrained amino acid surrogate or a conformational constraint element in the design of peptide-like molecules.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized as a scaffold for creating tool compounds and probes to study biological pathways and protein function.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-Boc-2-Methoxypiperidine
CAS No.	195964-51-3
Molecular Formula	C12H23NO3
Molecular Weight	229.32 g/mol
Synonyms	1-Boc-2-Methoxy-piperidine; tert-Butyl 2-methoxypiperidine-1-carboxylate; 2-Methoxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-2-methoxypiperidine; N-Boc-2-methoxypiperidine; 2-Methoxy-N-Boc-piperidine; Piperidine, 2-methoxy-, 1-(1,1-dimethylethyl) ester; 1,1-Dimethylethyl 2-methoxypiperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-Boc-2-Methoxypiperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.