Description

1-(2,6-Difluorophenyl)-1H-Pyrrole-2-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its difluorophenyl and nitrile-substituted pyrrole core. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored electronic and steric properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl moiety.
• Material Science: Used in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-withdrawing nitrile group and aromatic system.
• Chemical Synthesis: Functions as a versatile synthon for constructing more complex heterocyclic frameworks through reactions like cross-coupling, cyclization, and functional group transformations.
• Life Science Reagents: Employed in biochemical research as a probe or labeling agent precursor, exploiting its specific molecular recognition properties.

Basic Information

Product Name	1-(2,6-Difluorophenyl)-1H-Pyrrole-2-Carbonitrile
CAS No.	195711-28-5
Molecular Formula	C11H6F2N2
Molecular Weight	204.18 g/mol
Synonyms	1-(2,6-Difluorophenyl)-1H-pyrrole-2-carbonitrile; 1H-Pyrrole-2-carbonitrile, 1-(2,6-difluorophenyl)-; 2-Cyano-1-(2,6-difluorophenyl)pyrrole; 195711-28-5; 1-(2,6-Difluorophenyl)pyrrole-2-carbonitrile; 1-(2,6-Difluorophenyl)-2-cyanopyrrole
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)-1H-Pyrrole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.