Description

2-Fluoro-5-Nitrophenylacetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound matters as a versatile intermediate, enabling the introduction of both fluorine and nitro functional groups into target molecules, which is critical for modulating their biological activity and physicochemical properties. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal compounds used in display technologies.
• Peptide Mimetics & Bioconjugation: The carboxylic acid functionality allows for coupling reactions to create peptide analogs or for use in linker chemistry for bioconjugates.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new fluorination reactions and nitro group transformations.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized nitro- and fluoro-substituted dyes.

Basic Information

Product Name	2-Fluoro-5-Nitrophenylacetic Acid
CAS No.	195609-18-8
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	(2-Fluoro-5-nitrophenyl)acetic Acid; 2-(2-Fluoro-5-nitrophenyl)acetic Acid; α-(2-Fluoro-5-nitrophenyl)acetic Acid; 2-Fluoro-5-nitrobenzeneacetic Acid; NSC 405124; 195609-18-8; FNOA
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Nitrophenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure compliance with exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.