Description

3-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or host materials for OLED devices.
• Specialty Polymer Modifier: Incorporated to introduce fluorine functionality, improving chemical resistance and surface properties of polymers.
• Chemical Research & Development: A versatile building block for medicinal chemistry, facilitating structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid
CAS No.	195447-79-1
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	[3-Fluoro-5-(trifluoromethyl)phenyl]acetic Acid; 2-[3-Fluoro-5-(trifluoromethyl)phenyl]acetic Acid; α-(3-Fluoro-5-trifluoromethylphenyl)acetic Acid; 3-Fluoro-5-trifluoromethylphenylacetic Acid; 3-Fluoro-5-(trifluoromethyl)benzeneacetic Acid; (3-Fluoro-5-(trifluoromethyl)phenyl)acetic acid; 195447-79-1 (CAS)
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethyl)Phenylacetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.