Description

2H-1-Benzopyran-2-One, 4-Methyl-7-(2,3,5-Tri-o-Benzoyl-.Beta.-D-Ribofuranosyl)Oxy- is a key benzoylated ribofuranosyl derivative of a coumarin scaffold, serving as a critical protected intermediate in nucleoside and carbohydrate chemistry. Its primary value lies in enabling precise synthetic pathways for the development of novel pharmaceutical compounds and bioactive molecules. This high-purity intermediate is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, biotechnology, and fine chemical sectors focused on antiviral, anticancer, and other therapeutic agent synthesis.

Application

• Pharmaceutical Intermediate: A crucial protected building block in the multi-step synthesis of novel nucleoside analogs and prodrugs.
• Antiviral Drug Research: Used in the development of potential therapeutic agents targeting viral polymerases and replication mechanisms.
• Anticancer Agent Synthesis: Serves as a precursor for compounds being investigated for their cytotoxic or cell cycle inhibition properties.
• Carbohydrate Chemistry: Employed in the study and synthesis of complex, modified sugar derivatives and glycosylation reactions.
• Bioconjugation & Probe Development: Utilized to create fluorescent or bioactive probes for biochemical and cellular studies.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).

Basic Information

Product Name	2H-1-Benzopyran-2-One, 4-Methyl-7-(2,3,5-Tri-o-Benzoyl-.Beta.-D-Ribofuranosyl)Oxy-
CAS No.	195385-92-3
Molecular Formula	C36H28O10
Molecular Weight	620.60 g/mol
Synonyms	4-Methyl-7-((2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy)-2H-chromen-2-one; 4-Methyl-7-((2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy)coumarin; 7-((2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)oxy)-4-methylcoumarin; Tri-O-benzoyl-4-methylumbelliferone ribofuranoside; β-D-Ribofuranoside, 4-methyl-7-((2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy)-2H-1-benzopyran-2-one; Protected 4-MU riboside; 4-MU-β-D-ribofuranoside tri-benzoate
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and traceability. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and spectroscopic methods (NMR, MS) for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.