Description

2-(n-Benzyl-2,2,2-Trifluoroacetamido)Acetic Acid is a specialized trifluoroacetamide derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a benzyl-protected amine and a reactive acetic acid moiety, makes it a versatile building block for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those requiring trifluoromethylated or benzyl-protected motifs.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics, where the trifluoroacetamido group can influence metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a building block for developing advanced herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis and metal complexation.
• Material Science Precursor: Utilized in the synthesis of specialty polymers and advanced materials with specific surface properties or fluorine content.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	2-(n-Benzyl-2,2,2-Trifluoroacetamido)Acetic Acid
CAS No.	195254-57-0
Molecular Formula	C11H10F3NO3
Molecular Weight	261.20 g/mol
Synonyms	N-Benzyl-2,2,2-trifluoroacetamidoacetic Acid; 2-[(Benzylcarbamoyl)trifluoro]acetic Acid; (Benzylamino)(oxo)acetic Acid Trifluoro Derivative; Acetic acid, 2-[[(phenylmethyl)amino](trifluoroacetyl)amino]-; N-(Benzyl)-N-(carboxymethyl)trifluoroacetamide; BTFAA; 2-(N-Benzyltrifluoroacetamido)acetic Acid
EINECS	Contact for details

Quality Control

Our production of 2-(n-Benzyl-2,2,2-Trifluoroacetamido)Acetic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support development and cGMP-grade requirements for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.