Description

2-Pyrrolidinecarboxamide,n-Methoxy-n-Methyl-5-Oxo-,(2S)-(9Ci) is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex molecules with defined stereochemistry, which is critical for achieving desired biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, particularly for projects requiring precise stereochemical control. The product is supplied under stringent quality control to ensure batch-to-batch consistency for critical synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the multi-step synthesis of potential drug candidates, especially those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Used as a starting material or advanced intermediate in catalytic asymmetric reactions to introduce the (2S) pyrrolidinone scaffold.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics and protease inhibitors due to its proline-like structure.
• Agrochemical Development: Acts as a building block for creating novel chiral compounds with potential herbicidal or insecticidal activity.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological development in synthetic organic chemistry.
• Custom Synthesis: Provides a foundation for contract research organizations (CROs) and CDMOs to manufacture bespoke compounds for client projects.

Basic Information

Item	Detail
Product Name	2-Pyrrolidinecarboxamide,n-Methoxy-n-Methyl-5-Oxo-,(2S)-(9Ci)
CAS No.	195138-76-2
Molecular Formula	C8H14N2O3
Molecular Weight	186.21 g/mol
Synonyms	(2S)-N-Methoxy-N-methyl-5-oxopyrrolidine-2-carboxamide; (S)-N-Methoxy-N-methyl-5-oxopyrrolidine-2-carboxamide; (S)-5-Oxo-N-methoxy-N-methylpyrrolidine-2-carboxamide; (S)-Weinreb amide of 5-oxopyrrolidine-2-carboxylic acid; L-Pyroglutamic acid N,O-dimethylhydroxamate; (S)-Pyroglutamic acid Weinreb amide; (2S)-1-(Methoxy(methyl)carbamoyl)pyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinecarboxamide,n-Methoxy-n-Methyl-5-Oxo-,(2S)-(9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. Our quality protocols are designed to support cGMP and ISO guided processes for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.