Description

(S)-5-[(Biphenyl-4-Yl)Carbonyl]Pyrrolidin-2-One is a high-purity, chiral organic compound featuring a biphenyl carbonyl moiety attached to a pyrrolidinone scaffold. This specific stereochemistry and molecular architecture make it a critical intermediate for the synthesis of advanced pharmaceutical agents and bioactive molecules. It is primarily sought after by research institutions and pharmaceutical development teams working on novel therapeutics, particularly in areas requiring enantiomerically pure building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecules with defined three-dimensional structures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Biochemical Tool Compound: Potential use in developing enzyme inhibitors or receptor modulators for biochemical and pharmacological screening.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals and advanced materials requiring high purity and specific chirality.

Basic Information

Product Name	(S)-5-[(Biphenyl-4-Yl)Carbonyl]Pyrrolidin-2-One
CAS No.	195137-95-2
Molecular Formula	C17H15NO2
Molecular Weight	265.31 g/mol
Synonyms	(S)-5-(4-Phenylbenzoyl)-2-pyrrolidinone; (5S)-5-[(1,1'-Biphenyl]-4-ylcarbonyl]-2-pyrrolidinone; (S)-5-(Biphenyl-4-carbonyl)pyrrolidin-2-one; Biphenyl-4-yl((S)-2-oxopyrrolidin-5-yl)methanone; (S)-5-(4-Biphenylcarbonyl)-2-pyrrolidinone; (S)-5-(4-Biphenyloyl)-2-pyrrolidone; (S)-5-(Biphenyl-4-carbonyl)-2-pyrrolidone
EINECS	Contact for details

Quality Control

Our (S)-5-[(Biphenyl-4-Yl)Carbonyl]Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) documenting identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.