Description

1,3-Dimethoxy-2,4-difluorobenzene is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active ingredients, specialty chemicals, and functional materials that require precise fluorination.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a difluorinated aromatic core.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal stability, solubility, and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination methodologies and novel compound libraries.

Basic Information

Product Name	1,3-Dimethoxy-2,4-difluorobenzene
CAS No.	195136-69-7
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	2,4-Difluoro-1,3-dimethoxybenzene; 1,3-Dimethoxy-2,4-difluorobenzol; Benzene, 1,3-dimethoxy-2,4-difluoro-; 2,4-Difluororesorcinol dimethyl ether
EINECS	Contact for details

Quality Control

Our 1,3-Dimethoxy-2,4-difluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.