Description

Benzene, 2-Fluoro-1,3-Dimethoxy- (9Ci) is a fluorinated dimethoxybenzene derivative, a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and materials science industries seeking to introduce fluorine atoms into target molecules to modulate their biological activity, stability, or physical characteristics.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of active pharmaceutical ingredients (APIs), particularly for introducing fluorine into drug candidates to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve pesticidal activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Acts as a precursor for fluorinated aromatic cores in the synthesis of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs), influencing charge transport and emission properties.
• Polymer & Resin Modifier: Employed to create fluorinated monomers or additives that impart desirable characteristics such as enhanced chemical resistance, lower surface energy, or improved thermal stability to polymers.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Stille), nucleophilic aromatic substitution, and other transformations to construct complex, fluorinated aromatic systems for various R&D applications.
• Chemical Research & Development: Provides a standardized, high-purity starting material for method development and exploratory chemistry in academic and industrial laboratories.

Basic Information

Product Name	Benzene, 2-Fluoro-1,3-Dimethoxy- (9Ci)
CAS No.	195136-68-6
Molecular Formula	C8H9FO2
Molecular Weight	156.15 g/mol
Synonyms	1,3-Dimethoxy-2-fluorobenzene; 2-Fluoro-1,3-dimethoxybenzene; 2-Fluororesorcinol dimethyl ether; 2-Fluoro-1,3-bis(methyloxy)benzene; 2-Fluorobenzene-1,3-diol dimethyl ether; 2-Fluororesorcinol dimethyl ether; 2-Fluoro-1,3-dimethoxy-benzene
EINECS	Contact for details

Quality Control

Our Benzene, 2-Fluoro-1,3-Dimethoxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles as determined by techniques including GC, HPLC, and NMR. We support custom synthesis and can tailor specifications to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C/59-77°F). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥97.0%
Purity (GC Area %)	≥98.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.